Engineered immune cells take aim at Hard-to-Treat cancers

NCT ID NCT06885697

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 28 times

Summary

This early-phase study tests a new treatment called TNhYP218 CAR T cells for people with solid tumors, including mesothelioma, that have not responded to standard therapy. The treatment involves collecting a patient's own immune cells, modifying them in a lab to recognize and attack cancer cells with high levels of mesothelin, and infusing them back. The main goals are to find a safe dose and see if the treatment can shrink tumors.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.