Weekly shot shows promise for teen weight loss and health

NCT ID NCT06439277

Recruiting now Disease control Sponsor: Eli Lilly and Company Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 24 times

Summary

This study tests a once-weekly medicine called tirzepatide in 300 teens with obesity and at least two weight-related health issues like high blood pressure or prediabetes. Participants receive the drug or a placebo along with healthy eating and exercise advice for about 76 weeks. The goal is to see if the drug helps lower body mass index and improve overall health.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Addenbrooke's Hospital
RECRUITING

Cambridge, CB2 0SL, United Kingdom

Contact
Alberta Children's Hospital
RECRUITING

Calgary, T3B 6A8, Canada

Contact Phone: •••-•••-••••

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Alder Hey Children's Hospital
RECRUITING

Liverpool, L14 5AB, United Kingdom

Contact
Alliance for Multispecialty Research, LLC
COMPLETED

Layton, Utah, 84041, United States
Ann & Robert H. Lurie Children's Hospital of Chicago
ACTIVE_NOT_RECRUITING

Chicago, Illinois, 60611, United States
Assistance Publique - Hopitaux de Paris (AP-HP) - Hopital Robert Debre - Centre Hospitalo Universitaire (C -T
ACTIVE_NOT_RECRUITING

Paris, 75019, France
Assistance Publique Hôpitaux de Marseille - Hôpital de la Timone
ACTIVE_NOT_RECRUITING

Marseille, 13385, France
Bluewater Clinical Research Group Inc.
COMPLETED

Sarnia, N7T 4X3, Canada
CHU de Toulouse - Hôpital des Enfants
COMPLETED

Toulouse, 31059, France
Carmel Hospital
ACTIVE_NOT_RECRUITING

Haifa, 3436212, Israel
CenExel iResearch, LLC
RECRUITING

Decatur, Georgia, 30030, United States

Contact Phone: •••-•••-••••

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Centre Hospitalier Universitaire d'Angers
ACTIVE_NOT_RECRUITING

Angers, 49933, France
Centro Medico Dra. Laura Maffei- Investigacion Clinica Aplicada
RECRUITING

Buenos Aires, C1425AGC, Argentina

Contact Phone: •••-•••-••••

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Centro de Atención e Investigación Clínica
RECRUITING

Aguascalientes, 20129, Mexico

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Centro de Investigacion Medica de Occidente, S.C.
RECRUITING

Guadalajara, 44260, Mexico

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Centro de Investigaciones Metabólicas (CINME)
RECRUITING

Buenos Aires, C1056ABI, Argentina

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Centro de Investigaciones Médicas Tucuman
RECRUITING

SAN M. de Tucuman, T4000AXL, Argentina

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Chang Gung Medical Foundation-Linkou Branch
ACTIVE_NOT_RECRUITING

Taoyuan, 333, Taiwan
Children's Hospital Los Angeles
ACTIVE_NOT_RECRUITING

Los Angeles, California, 90027, United States
China Medical University Hospital
ACTIVE_NOT_RECRUITING

Taichung, 404332, Taiwan
Christus - Latam Hub Center of Excellence and Innovation S.C.
RECRUITING

Monterrey, 64060, Mexico

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Clínica García Flores SC
RECRUITING

Monterrey, 64610, Mexico

Contact Phone: •••-•••-••••

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Consano Clinical Research, LLC
ACTIVE_NOT_RECRUITING

Shavano Park, Texas, 78231, United States
Consultorio Médico de Endocrinología y Pediatría
RECRUITING

Puebla City, 72190, Mexico

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Cornerstone Dermatology
RECRUITING

Coorparoo, 4151, Australia

Contact Phone: •••-•••-••••

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DIM Clínica Privada
RECRUITING

Ramos Mejía, B1704ETD, Argentina

Contact Phone: •••-•••-••••

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Driscoll Children's Hospital
ACTIVE_NOT_RECRUITING

Corpus Christi, Texas, 78411, United States
Emek Medical Center
ACTIVE_NOT_RECRUITING

Afula, 1834111, Israel
Epic Medical Research - DeSoto
ACTIVE_NOT_RECRUITING

DeSoto, Texas, 75115, United States
Fundación Respirar
NOT_YET_RECRUITING

Buenos Aires, C1426ABP, Argentina

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H.R.U Málaga - Hospital General
ACTIVE_NOT_RECRUITING

Málaga, 29011, Spain
Hospices Civils de Lyon - Hopital Louis Pradel
ACTIVE_NOT_RECRUITING

Bron, 69677, France
Hospital Infantil Universitario Niño Jesús
ACTIVE_NOT_RECRUITING

Madrid, 28009, Spain
Hospital Universitari Vall d'Hebron
ACTIVE_NOT_RECRUITING

Barcelona, 08035, Spain
Hospital Universitari i Politecnic La Fe
ACTIVE_NOT_RECRUITING

Valencia, 46026, Spain
Hospital Universitario Reina Sofia
ACTIVE_NOT_RECRUITING

Córdoba, 14004, Spain
Hunter Medical Research Institute
RECRUITING

Newcastle, 2305, Australia

Contact Phone: •••-•••-••••

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Hôpital Armand Trousseau
ACTIVE_NOT_RECRUITING

Paris, 75012, France
Hôpital Jeanne de Flandre
ACTIVE_NOT_RECRUITING

Lille, 59000, France
Indiana University Health University Hospital
ACTIVE_NOT_RECRUITING

Indianapolis, Indiana, 46202, United States
Investigaciones Medicas Imoba Srl
RECRUITING

Buenos Aires, C1056ABH, Argentina

Contact Phone: •••-•••-••••

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Leeds General Infirmary
RECRUITING

Leeds, LS1 3EX, United Kingdom

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Leicester Royal Infirmary
RECRUITING

Leicester, LE1 5WW, United Kingdom

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Medical Research Partners
ACTIVE_NOT_RECRUITING

Ammon, Idaho, 83406, United States
Meir Medical Center
ACTIVE_NOT_RECRUITING

Kfar Saba, 4428164, Israel
National Cheng Kung University Hospital
ACTIVE_NOT_RECRUITING

Tainan, 704, Taiwan
National Taiwan University Hospital
COMPLETED

Taipei, 10002, Taiwan
Nemours Children's Health - Delaware
ACTIVE_NOT_RECRUITING

Wilmington, Delaware, 19803, United States
Nightingale Research
RECRUITING

Adelaide, 5000, Australia

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Paediatric and Adolescent OutpatientsElizabeth Garrett Anderson WingUniversity College Hospital
RECRUITING

London, WC1E 6DB, United Kingdom

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Perth Children's Hospital
RECRUITING

Perth, 6009, Australia

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Premier Clinical Trial Network
NOT_YET_RECRUITING

Hamilton, L8L5G4, Canada

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Rambam Health Care Campus
ACTIVE_NOT_RECRUITING

Haifa, 3109601, Israel
Royal Hospital for Children
RECRUITING

Glagow, G51 4TF, United Kingdom

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Royal Victoria Infirmary
RECRUITING

Newcastle upon Tyne, NE1 4PL, United Kingdom

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SUNY Upstate Medical University
ACTIVE_NOT_RECRUITING

Syracuse, New York, 13210, United States
Schneider Children's Medical Center
ACTIVE_NOT_RECRUITING

Petah Tikva, 4920235, Israel
Shaare Zedek Medical Center
COMPLETED

Jerusalem, 9013102, Israel
Sheba Medical Center
ACTIVE_NOT_RECRUITING

Ramat Gan, 5262100, Israel
Sheffield Children's Hospital
RECRUITING

Sheffield, S10 2TH, United Kingdom

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Soroka Medical Center
ACTIVE_NOT_RECRUITING

Beersheba, 8410101, Israel
Southampton General Hospital
RECRUITING

Southampton, SO16 6YD, United Kingdom

Contact Phone: •••-•••-••••

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Sutter Valley Medical Foundation (SVMF) Pediatric Endocrinology
ACTIVE_NOT_RECRUITING

Sacramento, California, 95821, United States
Texas Valley Clinical Research
ACTIVE_NOT_RECRUITING

Weslaco, Texas, 78596, United States
UBMD Pediatrics
ACTIVE_NOT_RECRUITING

Buffalo, New York, 14203, United States
Universitaetsklinikum Koeln
ACTIVE_NOT_RECRUITING

Cologne, 50937, Germany
Universitaetsklinikum Ulm
ACTIVE_NOT_RECRUITING

Ulm, 89075, Germany
University Pediatric Hospital
COMPLETED

San Juan, 00935, Puerto Rico
University of Sydney - Charles Perkins Centre
RECRUITING

Sydney, 2006, Australia

Contact
Universitätsklinikum Leipzig
ACTIVE_NOT_RECRUITING

Leipzig, 04103, Germany
Valley Institute of Research - Fort Worth
ACTIVE_NOT_RECRUITING

Fort Worth, Texas, 76164, United States
Winterberry Research Inc.
RECRUITING

Hamilton, L8J 0B6, Canada

Contact Phone: •••-•••-••••

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Yitzhak Shamir Medical Center
COMPLETED

Beer Yaacov, 70300, Israel

Conditions

Explore the condition pages connected to this study.

OBESITY WEIGHT GAIN