New knee injection could ease arthritis pain without surgery

NCT ID NCT03291470

First seen Jan 08, 2026 · Last updated May 15, 2026 · Updated 18 times

Summary

This study tested a single injection called TG-C for people with moderate knee osteoarthritis. 531 adults aged 40 and older received either TG-C or a placebo and were followed for 2 years. The goal was to see if the injection improves knee function and reduces pain better than a placebo.

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Contacts and locations

Locations

  • Bassil Aish

    Huntington Beach, California, 92647, United States

  • David Scott

    Spokane, Washington, 99218, United States

  • Duane Anderson

    San Diego, California, 92120, United States

  • Durga Tanneru

    Dallas, Texas, 75230, United States

  • Edward Tavel

    Charleston, South Carolina, 29406, United States

  • Haresh Boghara

    Red Oak, Texas, 75154, United States

  • Igor Grosman

    Brooklyn, New York, 11235, United States

  • Jan Hommen

    Doral, Florida, 33126, United States

  • Jeremy Hoff

    Wilmington, North Carolina, 28412, United States

  • Jonathan Samuels

    New York, New York, 10016, United States

  • Larkin Wadsworth

    St Louis, Missouri, 63141, United States

  • Leonel Reyes

    San Antonio, Texas, 78215, United States

  • Lisa Blair

    San Antonio, Texas, 78229, United States

  • Manjoo Sharma

    Lewisville, Texas, 75057, United States

  • Miguel Trevino

    Clearwater, Florida, 33756, United States

  • Minal Desai

    Durham, North Carolina, 27704, United States

  • Mira Baron

    West Palm Beach, Florida, 33409, United States

  • Nathan Rimmke

    Rochester Hills, Michigan, 48307, United States

  • Nebojsa Skrepnik

    Tucson, Arizona, 85712, United States

  • Peter Hanson

    La Mesa, California, 91942, United States

  • Priyesh Mehta

    Dayton, Ohio, 45432, United States

  • Richard Radnovich

    Boise, Idaho, 83713, United States

  • Robby Ann Quintos

    Las Vegas, Nevada, 89109, United States

  • Samy Metyas

    Covina, California, 91722, United States

  • Steve Sitar

    Anaheim, California, 92801, United States

  • Stuart Silverman

    Beverly Hills, California, 90211, United States

  • Thomas Schnitzer

    Chicago, Illinois, 60611, United States

Conditions

Explore the condition pages connected to this study.