Scientists probe brain synapses to unlock secrets of mental illness

NCT ID NCT07234851

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at brain tissue and lab-grown nerve cells from people with schizophrenia, depression, bipolar disorder, frontotemporal dementia, and Alzheimer's. Researchers want to find out how problems with synapses—the connections between brain cells—differ in these conditions. The goal is to better understand what goes wrong in the brain, which could guide future treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could reveal new targets for future treatments for several mental and neurodegenerative disorders.

What could go wrong

This is an observational study using stored tissue and cells, not a treatment trial. Findings may not directly lead to therapies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease behavioral variant of frontotemporal dementia bipolar disorder major depressive disorder neurodegenerative disease Pick disease psychiatric disorder schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Research Institute Sant Pau

    Barcelona, 08025, Spain