Scientists probe brain synapses to unlock secrets of mental illness

NCT ID NCT07234851

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at brain tissue and lab-grown nerve cells from people with schizophrenia, depression, bipolar disorder, frontotemporal dementia, and Alzheimer's. Researchers want to find out how problems with synapses—the connections between brain cells—differ in these conditions. The goal is to better understand what goes wrong in the brain, which could guide future treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this research could reveal new targets for future treatments for several mental and neurodegenerative disorders.
What could go wrong
This is an observational study using stored tissue and cells, not a treatment trial. Findings may not directly lead to therapies.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Research Institute Sant Pau

    Barcelona, 08025, Spain

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Other studies related to the condition(s) this trial covers.