Heart attack survivors' kidneys under microscope in massive study

NCT ID NCT07579390

Ongoing Knowledge-focused Sponsor: Helsinki University Central Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study examines how different hospital treatments—sedation, temperature control, and blood pressure management—after a cardiac arrest impact kidney function. Researchers will follow 3500 adults who were resuscitated from a heart attack outside the hospital. The goal is to understand which approaches lead to fewer kidney complications, not to test a new drug or cure.

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Conditions

The condition(s) this trial relates to.

acute kidney injury cardiac arrest Fever hypertensive disorder Out-of-Hospital Cardiac Arrest sudden cardiac arrest

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE KIDNEY FAILURE BLOOD PRESSURE CARDIAC ARREST (CA) FEVER MEAN ARTERIAL PRESSURE TARGETS OUT-OF-HOSPITAL CARDIAC ARREST RENAL REPLACEMENT THERAPY FOR ACUTE KIDNEY INJURY IN ICU RESUSCITATED SUDDEN CARDIAC DEATH SEDATION IN INTENSIVE CARE SEDATION IN INTENSIVE CARE UNIT PATIENTS SEDATION IN THE ICU TEMPERATURE

Contacts and locations

Locations

Austin Hospital

Melbourne, Australia
Bern University Hospital

Bern, Switzerland
Bristol Royal Infirmary

Bristol, United Kingdom
Cardiff University Hospital

Cardiff, United Kingdom
Centre Hospitalier de Luxembourg

Luxembourg, Luxembourg
Charite University Hospital

Berlin, Germany
Christchurch Hospital

Christchurch, New Zealand
DCCM ICU

Auckland, New Zealand
Essex Cardiothoracic Centre

Basildon, United Kingdom
Ghent University Hospital

Ghent, Belgium
HUB Hôpital Erasme

Brussels, Belgium
Hallands hospital

Halmstad, Sweden
Helsingborg Hospital

Helsingborg, Sweden
Jorvi Hospital

Espoo, Finland
Jyväskylä Hospital

Jyväskylä, Finland
Kalnes Hospital

Grålum, Norway
Karlstad hospital

Karlstad, Sweden
Karolinska University Hospital

Stockholm, Sweden
King Abdulaziz Medical City

Riyadh, Saudi Arabia
Kings College Hospita

London, United Kingdom
Kuopio University Hospital

Kuopio, Finland
Leeds General Infirmary

Leeds, United Kingdom
Liverpool Hospital

Liverpool, Australia
Lübeck University Hospital

Lübeck, Germany
Meilahti Hospital

Helsinki, 00290, Finland
Middlemore ICU

Auckland, New Zealand
Nepean Hospital

Kingswood, Australia
North Estonia Medical Centre

Tallinn, Estonia
North Shore ICU NZ

Auckland, New Zealand
Oslo University Hospital

Oslo, Norway
Oulu University Hospital

Oulu, Finland
Princess Alexandra Hospital

Brisbane, Australia
Royal North Shore Hospital

Sydney, Australia
Sahlgrenska University Hospital

Gothenburg, Sweden
San Martino Hospital Genova

Genova, Italy
Skaraborg Hospital Skovde

Skövde, Sweden
Skåne University Hospital

Lund, Sweden
Skåne University Hospital Malmö

Malmö, Sweden
Soerlandet Hospital Arendal

Arendal, Norway
St Bartholomew's Hospital

London, United Kingdom
St Gallen Hospital

Sankt Gallen, Switzerland
St George Hospital

Sydney, Australia
St Georges University Hospital

London, United Kingdom
Stavanger University Hospital

Stavanger, Norway
Tan Tock Seng Hospital

Singapore, Singapore
The Prince Charles Hospital

Brisbane, Australia
The Sutherland Hospital

Sydney, Australia
Tubingen University Hospital

Tübingen, Germany
University Hospital Zürich

Zurich, Switzerland
University Hospital of Umeå

Umeå, Sweden
Wellington Hospital

Wellington, New Zealand
Ziekenhuis Oost-Limburg Hospital

Lanaken, Belgium

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