Could umbilical cord stem cells ease knee arthritis pain?

NCT ID NCT03383081

Recruiting now Disease control Sponsor: Sclnow Biotechnology Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether stem cells from umbilical cords can help people with knee osteoarthritis. Sixty participants will receive either a low or high dose of these cells injected into the knee joint. The goal is to see if the treatment is safe and can reduce pain and improve knee function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: human umbilical cord mesenchymal stem cells
What this could lead to: If it works, this could provide a new treatment to control knee osteoarthritis, reducing pain and potentially delaying or avoiding joint replacement surgery.
What could go wrong: This is an early phase 2 trial with only 60 people, so results may not apply to everyone. Stem cell treatments can have side effects like infection or immune reactions, and the long-term benefits are still unknown.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEOARTHRITIS, KNEE

Contacts and locations

Locations

Xiangya Hospital Central South University
RECRUITING

Changsha, Hunan, 410008, China

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