Could umbilical cord stem cells ease knee arthritis pain?

NCT ID NCT03383081

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether stem cells from umbilical cords can help people with knee osteoarthritis. Sixty participants will receive either a low or high dose of these cells injected into the knee joint. The goal is to see if the treatment is safe and can reduce pain and improve knee function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

human umbilical cord mesenchymal stem cells

What this could lead to

If it works, this could provide a new treatment to control knee osteoarthritis, reducing pain and potentially delaying or avoiding joint replacement surgery.

What could go wrong

This is an early phase 2 trial with only 60 people, so results may not apply to everyone. Stem cell treatments can have side effects like infection or immune reactions, and the long-term benefits are still unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Xiangya Hospital Central South University

    RECRUITING

    Changsha, Hunan, 410008, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••