Could a single shot of your own stem cells ease knee arthritis?
NCT ID NCT02838069
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tested whether a single injection of a patient's own fat-derived stem cells can reduce pain and improve knee function in people with mild to moderate knee osteoarthritis that hasn't responded to other treatments. One hundred participants received either a low dose, a high dose, or a placebo injection. Researchers measured pain and function improvements over 6 to 24 months using questionnaires and MRI scans.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a patient's own fat-derived stem cells (called mesenchymal stromal cells)
- What this could lead to
- If it works, this could offer a new, one-time injection to ease pain and improve knee function for people with mild to moderate osteoarthritis.
- What could go wrong
- This is a mid-stage trial with only 100 participants, so results may not apply to everyone. The treatment is still experimental, and long-term safety and effectiveness are not yet proven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
UH Montpellier
Montpellier, 34295, France
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