Could a common gut supplement boost weight loss in diabetes?

NCT ID NCT07252609

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether taking sodium butyrate tablets for 12 weeks, along with a modestly reduced-calorie diet, helps overweight or obese adults (with or without type 2 diabetes) lose more weight and improve blood sugar and fat levels compared to a placebo. 46 participants were randomly assigned to receive either the supplement or placebo. The study measured weight, body composition, and glucose control.

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Conditions

The condition(s) this trial relates to.

Body Weight Obesity obesity disorder type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Federico II University

    Naples, 80131, Italy