Could your sex change how Alzheimer's shows up in your blood?

NCT ID NCT07224139

Ongoing Knowledge-focused Sponsor: Anne Murray Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study uses blood samples and health data from over 13,000 older adults to see if Alzheimer's-related blood markers differ between men and women. Researchers aim to create a sex-specific risk score that could help predict the disease earlier and personalize future treatments. No new treatments are being tested; instead, the goal is to better understand how the disease progresses differently in each sex.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a personalized risk score for Alzheimer's that accounts for sex differences, improving early detection and clinical trial design.
What could go wrong: This is an observational analysis of existing data, not a treatment trial. The findings may not directly change clinical practice and require validation in other populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease cognitive disorder Cognitive Dysfunction dementia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALZHEIMER DISEASE COGNITIVE DYSFUNCTION DEMENTIA

Contacts and locations

Locations

Foundation for Atlanta Veterans Education and Research, Inc.

Decatur, Georgia, 30033, United States
Hennepin Healthcare Research Institute

Minneapolis, Minnesota, 55415, United States
Monash University

Melbourne, Victoria, 3800, Australia
Regents of the University of Minnesota - Advanced Research & Diagnostic

Minneapolis, Minnesota, 55455, United States
Wake Forest University

Winston-Salem, North Carolina, 27109, United States

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