Arm cuff procedure tested to fight organ failure in septic shock

NCT ID NCT03201575

Completed Disease control Sponsor: Hospices Civils de Lyon Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested whether a non-invasive arm cuff procedure, called remote ischemic conditioning, could reduce organ failure in 180 adults with septic shock. The cuff was inflated and deflated in cycles to mimic brief blood flow restriction. The goal was to see if this could protect organs from damage caused by the body's response to severe infection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Remote ischemic conditioning (arm cuff inflation/deflation cycles)
What this could lead to: If it works, this simple, non-drug technique could help limit organ damage in septic shock, potentially improving survival.
What could go wrong: This is a completed early-stage study with 180 patients. The intervention is experimental and may not show clear benefit; results need confirmation in larger trials.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

multiple organ dysfunction syndrome toxic shock syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SEPTIC SHOCK

Contacts and locations

Locations

CH de Roanne

Roanne, France
CHU de Clermont-Ferrand

Clermont-Ferrand, France
CHU de Grenoble

Grenoble, France
CHU de Montpellier

Montpellier, France
CHU de Saint-Etienne

Saint-Etienne, France
Hôpital Edouard Herriot

Lyon, France

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