Tiny lungs, big questions: can we tell which preemies benefit from water pills?
NCT ID NCT05898022
First seen Jun 27, 2026 · Last updated Jul 15, 2026 · Updated 2 times
Summary
This study looked at a new method to find out if diuretics (water pills) help individual premature babies with a chronic lung condition called bronchopulmonary dysplasia (BPD). Researchers enrolled 19 very premature infants and used a special 'N-of-1' approach, where each baby was switched between the drug and a placebo to see if they truly responded. The goal was to gather information to design a larger study, not to prove the drug works long-term.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Case Western Reserve University, Rainbow Babies and Children's Hospital
Cleveland, Ohio, 44106, United States
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229, United States
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Emory University
Atlanta, Georgia, 30303, United States
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RTI International
Durham, North Carolina, 27705, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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