New weekly shot shows promise for weight loss in type 2 diabetes
NCT ID NCT06926842
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This Phase 2 trial tests a once-weekly injection called petrelintide in 221 people with overweight or obesity and type 2 diabetes. Participants receive either petrelintide or a placebo for several weeks. The main goal is to see how much weight they lose and whether blood sugar improves.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
petrelintide (a once-weekly injection)
What this could lead to
If successful, this could lead to a new weekly injection that helps people with type 2 diabetes and overweight lose weight and improve blood sugar control.
What could go wrong
This is an early Phase 2 trial with only 221 people, so results may not apply to everyone. The drug may cause side effects or not work better than placebo.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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AAMRC
Flint, Michigan, 48504, United States
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AMR Kansas City
Kansas City, Missouri, 64114, United States
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AZ Endocrine Institute
Chandler, Arizona, 85224, United States
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Centricity Research
Columbus, Ohio, 43213, United States
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Chase Medical Research, LLC
Waterbury, Connecticut, 06708, United States
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Consano Clinical Research
Shavano Park, Texas, 78231, United States
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Cullman Clinical Trials - Family Medicine
Cullman, Alabama, 35055, United States
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DelRicht Research - New Orleans
New Orleans, Louisiana, 70115, United States
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Diablo Clinical Research Inc.
Walnut Creek, California, 94598, United States
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East Coast Institute for Research - Canton
Canton, Georgia, 30114, United States
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East Coast Institute for Research, LLC
Jacksonville, Florida, 32204, United States
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Elite Clinical Studies, LLC
Phoenix, Arizona, 85018, United States
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Elligo Clinical Research, Inc.
Austin, Texas, 78704, United States
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Emerson Clinical Research
Washington D.C., District of Columbia, 20009, United States
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Exalt Clinical Research
San Diego, California, 91910, United States
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Great Lakes Clinical Trials
Chicago, Illinois, 60640, United States
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Heartland Research Associates, LLC
Wichita, Kansas, 67207, United States
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Innovative Research of West Florida
Clearwater, Florida, 33756, United States
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International Diabetes Center
Minneapolis, Minnesota, 55416, United States
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Iowa Diabetes & Endocrinology Research Center
West Des Moines, Iowa, 50266, United States
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Javara Inc
Charlotte, North Carolina, 28210, United States
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Juno Research LLC
Houston, Texas, 77040, United States
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Lynn Institute of Norman
Norman, Oklahoma, 73072, United States
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M3 Wake Research
Raleigh, North Carolina, 27612, United States
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M3 Wake Research - Atlanta
Atlanta, Georgia, 30328, United States
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M3 Wake Research - Charleston
Charleston, South Carolina, 29414, United States
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M3 Wake Research - Lake City
Lake City, Florida, 32055, United States
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M3 Wake Research - Las Vegas, NV
Las Vegas, Nevada, 89106, United States
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M3 Wake Research, Tucson Neuroscience Research, LLC
Tucson, Arizona, 85710, United States
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M3 Wake Research/ClinSearch, LLC
Chattanooga, Tennessee, 37421, United States
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Manaasas Clinical Research Center
Manassas, Virginia, 20110, United States
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Medical Investigation Inc
Little Rock, Arkansas, 72211-1847, United States
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Mercury Street Medical Group, PLLC
Butte, Montana, 59701, United States
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Palm Beach Research Center
West Palm Beach, Florida, 33409, United States
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Palm Research Center, Inc.
Las Vegas, Nevada, 89148, United States
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PharmQuest Life Sciences, LLC
Greensboro, North Carolina, 27408, United States
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Privia Medical Group Georgia, LLC
Savannah, Georgia, 31406, United States
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Solutions Through Advanced Research, Inc
Jacksonville, Florida, 32216, United States
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Tekton Research, LLC
Irving, Texas, 75039, United States
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Tekton Research, LLC
McKinney, Texas, 75069, United States
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Texas Health Care
Stephenville, Texas, 76401, United States
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Texas Health Care, PLLC
San Marcos, Texas, 78666, United States
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The University of Texas Southwestern Medical Center
Dallas, Texas, 75390-8857, United States
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Velocity Clinical Research
Huntington Park, California, 90255, United States
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Velocity Clinical Research, Cincinnati, Mt. Auburn
Cincinnati, Ohio, 45219, United States
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Velocity Clinical Research, Gulfport
Gulfport, Mississippi, 39503, United States
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Velocity Clinical Research, North Hollywood
North Hollywood, California, 91606, United States
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West Orange Endocrinology P.A
Ocoee, Florida, 34761, United States