5-Day brain zaps aim to ease postpartum depression

NCT ID NCT06968390

Recruiting now Symptom relief Sponsor: Brigham and Women's Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests an accelerated form of Transcranial Magnetic Stimulation (TMS) for depression in pregnant and postpartum individuals. Instead of daily sessions for weeks, participants receive multiple treatments over just 5 days. The goal is to see if this faster approach is safe, tolerable, and practical for this group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Transcranial Magnetic Stimulation (TMS)
What this could lead to: If it works, this could offer a fast, non-invasive treatment option for depression during pregnancy and after childbirth, potentially easing symptoms in just 5 days.
What could go wrong: This is a very small early-stage trial with only 24 participants, focused on safety and tolerability, not yet on effectiveness. The treatment may not work for everyone, and there is a risk of side effects like seizures.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MAJOR DEPRESSIVE DISORDER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

major depressive disorder perinatal asphyxia postpartum depression

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MAJOR DEPRESSIVE DISORDER PERINATAL DEPRESSION POST PARTUM DEPRESSION

Contacts and locations

Locations

Brigham and Women's Hospital
RECRUITING

Boston, Massachusetts, 02115, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.