Parkinson's puzzle: does it start in the brain or the body?

NCT ID NCT07187843

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 150 people with early-stage Parkinson's disease to see if the condition starts in the brain or the body first. Researchers will track symptoms like walking problems and thinking changes over 5 years using tests, scans, and questionnaires. The goal is to better understand these two types of Parkinson's and pave the way for more personalized treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors better predict how Parkinson's disease will progress in each patient, leading to more personalized care and earlier, more targeted treatments.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly test a new therapy. The findings may not apply to all Parkinson's patients, and the 5-year follow-up may be too short to see full disease progression.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Azienda USL IRCCS di Reggio Emilia

    RECRUITING

    Reggio Emilia, Italy

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