Parkinson's puzzle: does it start in the brain or the body?

NCT ID NCT07187843

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 150 people with early-stage Parkinson's disease to see if the condition starts in the brain or the body first. Researchers will track symptoms like walking problems and thinking changes over 5 years using tests, scans, and questionnaires. The goal is to better understand these two types of Parkinson's and pave the way for more personalized treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help doctors better predict how Parkinson's disease will progress in each patient, leading to more personalized care and earlier, more targeted treatments.

What could go wrong

This is an observational study, not a treatment trial, so it won't directly test a new therapy. The findings may not apply to all Parkinson's patients, and the 5-year follow-up may be too short to see full disease progression.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

basal ganglia disorder brain disorder movement disorder nervous system disorder neurodegenerative disease Neuroinflammatory Diseases Parkinson disease parkinsonian disorder synucleinopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Azienda USL IRCCS di Reggio Emilia

    RECRUITING

    Reggio Emilia, Italy

    Contact Email: •••••@•••••