Azienda Usl Reggio Emilia - Irccs

This study is for people with advanced colorectal cancer that has a certain genetic makeup (RAS/BRAF wild type) in the tumor but shows a different genetic change (RAS mutation) in a blood test. The goal is to see if a combination of chemotherapy (FOLFIRI) plus a drug called bevac…

This study compares two minimally invasive procedures—EMR and ESD—for removing large, flat colon growths (LST-G) that can turn into cancer. About 282 adults will be randomly assigned to one of the two techniques. The goal is to see which method leads to fewer growths coming back …

This study tests whether a simple card game, called the Go Wish Game, can help people with advanced blood cancers or solid tumors talk about their end-of-life wishes with their doctors. About 75 adults with a life expectancy of more than 3 months will play the game and then compl…

This study uses artificial intelligence to detect when radioactive medicine leaks out of a vein during a scan or therapy. Researchers will measure radiation levels and develop computer models to identify leaks in real time. The goal is to improve safety and make sure images are a…

This study looks at a rare event where an aggressive lymphoma (DLBCL) comes back as a slow-growing (indolent) type. Researchers will review medical records of 50 adults to learn how often this happens, what tests can spot it, and how well different treatments work. The goal is to…

This study looks at how physically active cancer survivors are over time. It aims to understand what helps or stops them from being active. Researchers will track 50 adults with cancer who visit a special clinic that promotes exercise. The goal is to find better ways to support s…

This study reviews medical records of 4500 adults with mild head injury to see how often serious complications like brain bleeding occur. It compares two common rules (Canadian CT Head Rule and NEXUS) to see which better predicts problems. The goal is to improve emergency care an…

This observational study is looking for biological markers that can predict if early blood disorders (MGUS or SMM) will progress to multiple myeloma, a type of blood cancer. Researchers will analyze genetics, immune cells, and mouth bacteria from 60 patients and compare them to h…

This study looks at a very rare type of ovarian cancer called primary ovarian leiomyosarcoma. Researchers will collect information from past and new cases to understand how it is treated and what happens to patients. The goal is to create better guidelines for doctors. No new tre…

This study aims to create and test a new questionnaire for caregivers to assess hip pain in children with quadriplegia who cannot communicate verbally. Researchers will develop the tool with input from experts and parents, then validate it with 100 caregivers. The goal is to prov…

This study looks at how the immune system interacts with malignant pleural mesothelioma, a rare and hard-to-treat cancer. Researchers will analyze tumor samples from 300 patients to understand why current immunotherapies help only some people. The goal is to find new ways to make…

This study is looking for genetic targets in ovarian cancer, especially a common type called high-grade serous ovarian carcinoma. Researchers will study tissue samples from 180 women to find genes that might help diagnose or treat the disease. The goal is to better understand the…

This study follows 150 people with early-stage Parkinson's disease to see how symptoms like walking problems and thinking changes differ between two newly identified types: 'brain-first' and 'body-first.' Researchers will use brain scans, movement tests, and other assessments ove…

This study looks back at medical records of 2,000 adults who had endoscopic removal of cancerous or precancerous growths in the esophagus, stomach, duodenum, colon, or rectum. The goal is to compare different removal methods to see which is safest and most effective at completely…