Parkinson's gene mutation may raise cancer risk – large study investigates
NCT ID NCT06814431
First seen Jul 24, 2026 · Last updated Jul 24, 2026
Summary
This large observational study is investigating whether people with Parkinson's disease who carry a mutation in the GBA1 gene have a higher chance of developing cancer. Researchers will compare cancer rates in this group to those in Parkinson's patients without the mutation and to the general population. The goal is to understand if the GBA1 mutation, already linked to Gaucher disease, also increases cancer risk in Parkinson's patients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If a link is found, it could lead to better cancer screening and more comprehensive care for Parkinson's patients with this genetic mutation.
- What could go wrong
- This is an observational study, so it can show an association but not prove cause and effect. The results may not apply to all populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Azienda USL IRCCS di Reggio Emilia
RECRUITINGReggio Emilia, 42123, Italy
Contact
Contact Phone: •••-•••-••••
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IRCCS Istituto Neurologico Carlo Besta
RECRUITINGMilan, Italy
Contact Email: •••••@•••••
Contact
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Ospedale A. Perrino
RECRUITINGBrindisi, Italy
Contact Email: •••••@•••••
Contact
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Ospedale Santa Chiara di Trento
RECRUITINGTrento, Italy
Contact Email: •••••@•••••
Contact