Azienda Usl Reggio Emilia - Irccs

This study compares two procedures—EMR and ESD—for removing large, flat colon growths (called LST-G) that can turn into cancer. About 282 adults will be randomly assigned to one of the two methods. The goal is to see which technique leads to fewer growths coming back within a yea…

This study looks at people with advanced colorectal cancer whose tumor tissue shows no RAS/BRAF mutation, but a liquid biopsy (blood test) finds a RAS mutation. It compares two standard drug combos (FOLFIRI plus either cetuximab or bevacizumab) to see which works better at stoppi…

This study compares contrast-enhanced mammography (CEM) to the standard MRI plus digital mammography for screening women at high risk of breast cancer. About 2200 women aged 35-60 with a 5-year risk of 5% or higher will be randomly assigned to one of the two screening methods ove…

This study is creating and testing a new questionnaire for caregivers to identify hip pain in children with quadriplegia who cannot communicate verbally. Researchers will first develop the questionnaire with input from experts and parents, then test it with 100 caregivers. The go…

This study tests whether a simple card game, the Go Wish Game, can help people with advanced blood cancers or solid tumors discuss their end-of-life priorities with doctors. About 75 patients will use the cards to sort what matters most to them, then complete an advance care plan…

This study looks at whether a lung ultrasound score can help predict bronchopulmonary dysplasia (BPD), a serious lung condition, in premature babies born before 32 weeks. About 40% of extremely preterm infants develop BPD, which can cause long-term breathing problems. Researchers…

This observational study is looking for better ways to predict how Hodgkin lymphoma will progress. Researchers will analyze genetic material from tumor samples and blood tests, along with PET scan images, from 755 patients. The goal is to identify markers that could help doctors …

This study tests a new AI system that uses a special radiation detector to spot leaks when radioactive drugs are given to patients during PET scans or cancer therapy. The goal is to make these procedures safer and improve the quality of the images. Researchers will study 1,500 pa…

This study looks at a rare event where an aggressive lymphoma (DLBCL) comes back as a slow-growing (indolent) lymphoma. Researchers will review medical records of 50 adults to understand how often this happens, what treatments are used, and how well patients do. The goal is to ga…

This study is collecting information from 30 patients with an extremely rare ovarian cancer called primary ovarian leiomyosarcoma. Researchers will look at past and new cases to find patterns in how the cancer is diagnosed and treated. The goal is to create better guidelines for …

This study looks at the immune system inside malignant pleural mesothelioma, a rare and hard-to-treat cancer. Researchers will analyze tumor samples from 300 adults to understand why immunotherapy helps only some patients. The goal is to find clues that could make these treatment…

This study follows 150 people with early-stage Parkinson's disease to see if the condition starts in the brain or the body first. Researchers will track symptoms like walking problems and thinking changes over 5 years using tests, scans, and questionnaires. The goal is to better …

This study looks at people with early blood disorders (MGUS and smoldering myeloma) who are at risk of developing multiple myeloma, a type of bone marrow cancer. Researchers will use advanced genetic and immune testing on blood and bone marrow samples, along with mouth bacteria a…

This study follows 50 cancer survivors who visit the MO.RE clinic to see how their physical activity levels change over time. The clinic offers personalized advice and support from a physiotherapist to help patients overcome barriers like fatigue or lack of motivation. The goal i…

This study looks back at the records of 4,500 adults with mild head injuries treated in emergency rooms in the Emilia-Romagna region of Italy. Researchers want to see how often serious complications like brain bleeding occur and compare two common rules doctors use to decide if a…

This study looks back at medical records of 2000 adults who had endoscopic removal of cancerous or precancerous growths in the esophagus, stomach, duodenum, colon, or rectum. The goal is to compare different removal methods to see which works best and has the fewest complications…

This study looks at genetic targets in ovarian cancer, focusing on a common type called high-grade serous carcinoma. Researchers will analyze tumor tissue from 180 adult women to understand which genes are involved. The goal is to find new ways to diagnose or treat the disease, b…