Could a lifesaving leukemia drug harm Men's sexual health?

NCT ID NCT07061145

First seen Aug 07, 2026 ยท Last updated Aug 07, 2026

Summary

This study looks at whether tyrosine kinase inhibitors (TKIs), the standard treatment for chronic myeloid leukemia (CML), might be linked to erectile dysfunction (ED) in men. Researchers will track 350 male patients who started TKI therapy, using questionnaires and medical records to see how many develop ED and whether the type of TKI matters. The goal is to better understand the long-term side effects of these drugs and potentially improve patient care.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Tyrosine kinase inhibitors (TKIs) such as imatinib, dasatinib, nilotinib, bosutinib, or ponatinib, given as standard care for chronic myeloid leukemia.
What this could lead to
If a link is confirmed, it could lead to better monitoring and management of erectile dysfunction in men taking TKIs, improving quality of life and potentially aiding early detection of cardiovascular risk.
What could go wrong
This is an observational study, so it cannot prove cause and effect. The results may be influenced by other factors, and the findings might not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CHRONIC MYELOCYTIC LEUKEMIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Azienda USL IRCCS di Reggio Emilia

    RECRUITING

    Reggio Emilia, RE, 42121, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.