SYNUCLEINOPATHIES
Clinical trials for SYNUCLEINOPATHIES explained in plain language.
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Could a new drug slow lewy body dementia? phase 2 trial begins
Disease control Recruiting nowThis phase 2 trial tests whether donanemab, an antibody given by IV, can slow worsening of thinking and daily function in people with early cognitive decline and Lewy body dementia. The study enrolls 350 participants who also have signs of two brain proteins (amyloid and alpha-sy…
Matched conditions: SYNUCLEINOPATHIES
Phase: PHASE2 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Jul 19, 2026 00:00 UTC
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Step toward prevention: app-based exercise may protect the brain in Parkinson's risk group
Prevention Recruiting nowThis study tests whether increasing physical activity through a motivational smartphone app can slow cognitive decline in people with isolated REM sleep behavior disorder (iRBD), an early sign of Parkinson's disease and related disorders. Researchers will enroll 130 participants …
Matched conditions: SYNUCLEINOPATHIES
Phase: NA • Sponsor: University Hospital, Bonn • Aim: Prevention
Last updated Jun 27, 2026 08:11 UTC
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Parkinson's puzzle: does it start in the brain or the body?
Knowledge-focused Recruiting nowThis study follows 150 people with early-stage Parkinson's disease to see if the condition starts in the brain or the body first. Researchers will track symptoms like walking problems and thinking changes over 5 years using tests, scans, and questionnaires. The goal is to better …
Matched conditions: SYNUCLEINOPATHIES
Sponsor: Azienda USL Reggio Emilia - IRCCS • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Sleep study could unlock secrets of Parkinson's progression
Knowledge-focused Recruiting nowThis study follows 650 people with early Parkinson's disease or a sleep condition called idiopathic REM sleep behavior disorder (iRBD). Researchers use brain scans, heart tests, and fluid samples to track changes over time. The goal is to better understand how these conditions de…
Matched conditions: SYNUCLEINOPATHIES
Sponsor: Skane University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC