Pancreas cancer screening trial enrolls 9,000 High-Risk individuals

NCT ID NCT02000089

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 3 study is testing whether markers in pancreatic fluid and blood can detect early pancreas cancer in people with high genetic risk. Participants receive a secretin injection to collect fluid during an endoscopy. The goal is to improve early detection in those with hereditary pancreatitis, Peutz-Jeghers syndrome, strong family history, or certain gene mutations.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Secretin injection (ChiRhoStim) to collect pancreatic fluid for biomarker testing

What this could lead to

If successful, this could lead to a reliable screening method to catch pancreas cancer early in people with high genetic risk.

What could go wrong

This is a screening study, not a treatment. It may not prove that early detection improves survival, and false positives could cause unnecessary procedures.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast neoplasm Colorectal Neoplasms, Hereditary Nonpolyposis hereditary chronic pancreatitis hereditary sensory and autonomic neuropathy Lynch syndrome malignant pancreatic neoplasm melanoma, cutaneous malignant, susceptibility to, 2 pancreatic neoplasm Peutz-Jeghers syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Case Comprehensive Cancer Center, Case Western Medical Reserve

    RECRUITING

    Cleveland, Ohio, 44106, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Columbia University Medical Center

    RECRUITING

    New York, New York, 10032, United States

    Contact

    Contact Email: •••••@•••••

  • Dana Farber Cancer Center, Harvard University

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Johns Hopkins Hospital

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • NYU Langone Medical Center

    RECRUITING

    New York, New York, 10016, United States

    Contact Email: •••••@•••••

    Contact

  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

  • University of Pittsburgh

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

    Contact Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

  • Yale University

    RECRUITING

    New Haven, Connecticut, 06520, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••