Could a pacifier help babies with down syndrome breathe better at night?

NCT ID NCT07658053

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether a special pacifier, called CURAPROX, can reduce the severity of obstructive sleep apnea (OSA) in infants with Down syndrome. Fifty infants will be enrolled at one month old, with half using the pacifier and half not. At six months, sleep tests will measure breathing problems to see if the pacifier helps.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

CURAPROX biofunctional pacifier

What this could lead to

If it works, this could point toward a simple, low-cost way to prevent or reduce sleep apnea in infants with Down syndrome, potentially improving their development.

What could go wrong

This is a small, early-stage study with only 50 infants, so results may not apply to everyone. The pacifier may not reduce sleep apnea, and long-term benefits are unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Down syndrome sleep apnea syndrome obstructive sleep apnea syndrome prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hôpital Femme-Mère-Enfant, Service d'épileptologie clinique, des troubles du sommeil et de neurologie fonctionnelle de l'enfant

    Bron, 69500, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact