DOWN SYNDROME (TRISOMY 21)

This study is testing a new blood test that looks for fetal cells in the mother's blood to detect genetic conditions like Down syndrome. The test will be compared to standard diagnostic methods such as amniocentesis or newborn testing. The study involves 1,000 pregnant individual…

This study tests if the drug levetiracetam can prevent epileptic seizures in 120 adults over 40 with Down syndrome and Alzheimer's disease. Participants will receive either the drug or a placebo for 96 weeks. The goal is to see if the drug can stop seizures and possibly slow brai…

This study tests a new drug called AEF0217 to see if it can improve daily living skills in adults and older teens with Down Syndrome. About 188 participants will take either the drug or a placebo daily for 24 weeks. Researchers will check changes in behavior, thinking, and qualit…

This study tests a mindfulness-based therapy designed to improve sleep in people with Down syndrome (age 12+). The program is adapted with visual aids, shorter meditations, and caregiver support. Researchers will compare it to a brief behavioral therapy in 20 participants, measur…

This study looks at blood vessel health in adults with Down syndrome (ages 18-35) compared to adults without Down syndrome. Researchers want to find out if people with Down syndrome have hidden changes in their blood vessels that could raise their risk for heart disease or stroke…

This study looks at 30 six-month-old infants with Down syndrome to see if their sucking patterns are linked to the severity of obstructive sleep apnea (OSA). Researchers will measure sucking bursts and compare them to sleep study results. The goal is to find a simple way to scree…

This study looks at how a 2-week, personalized therapy program helps children aged 4-12 with conditions like cerebral palsy, autism, or genetic disorders. Kids get about 2.5 hours of tailored therapy each day, focusing on skills like movement, attention, and communication. The go…