DOWN SYNDROME (TRISOMY 21)
Clinical trials for DOWN SYNDROME (TRISOMY 21) explained in plain language.
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New hope: drug may stop seizures in down syndrome Alzheimer's patients
Prevention Recruiting nowThis study tests if levetiracetam, a seizure medication, can prevent epileptic seizures in 120 adults over 40 with Down syndrome and Alzheimer's disease. Participants will receive either the drug or a placebo for 96 weeks. The goal is to see if the drug can stop seizures and poss…
Matched conditions: DOWN SYNDROME (TRISOMY 21)
Phase: PHASE3 • Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau • Aim: Prevention
Last updated May 16, 2026 23:37 UTC
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New drug aims to boost daily living skills in down syndrome
Symptom relief Recruiting nowThis study tests whether a daily pill called AEF0217 can improve everyday skills like communication and self-care in adults and older teens with Down Syndrome. About 188 participants will take one of three doses of the drug or a placebo for 24 weeks. Researchers will check change…
Matched conditions: DOWN SYNDROME (TRISOMY 21)
Phase: PHASE2 • Sponsor: Aelis Farma • Aim: Symptom relief
Last updated May 16, 2026 23:51 UTC
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Mindfulness for better sleep in down syndrome: a new hope for families
Symptom relief Recruiting nowThis study aims to help young people with Down syndrome (age 12 and older) and their caregivers sleep better and feel better. Researchers will adapt a virtual mindfulness program for insomnia and test it in a small trial with 20 participants. The goal is to see if the therapy imp…
Matched conditions: DOWN SYNDROME (TRISOMY 21)
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Symptom relief
Last updated May 16, 2026 23:37 UTC
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Intensive therapy shows promise for kids with brain disorders
Symptom relief Recruiting nowThis study looks at how a 2-week, personalized therapy program helps children aged 4-12 with conditions like autism, cerebral palsy, or genetic disorders. Kids get about 2.5 hours of tailored therapy each day, focusing on skills like movement, attention, and communication. The go…
Matched conditions: DOWN SYNDROME (TRISOMY 21)
Sponsor: Healing Hope International • Aim: Symptom relief
Last updated May 12, 2026 13:44 UTC
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Baby's suck may predict sleep apnea risk in down syndrome
Knowledge-focused Recruiting nowThis study looks at 30 infants with Down syndrome who are 6 months old. Researchers want to see if the way babies suck (non-nutritive sucking) is linked to how severe their sleep apnea is. The goal is to find a simple way to screen for sleep apnea early, so babies can get help so…
Matched conditions: DOWN SYNDROME (TRISOMY 21)
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated May 14, 2026 12:02 UTC