Could a daily pill boost independence in down syndrome?

NCT ID NCT07334912

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new drug called AEF0217 to see if it can improve daily living skills in adults and older teens with Down Syndrome. About 188 participants will take either the drug or a placebo daily for 24 weeks. Researchers will check changes in behavior, thinking, and quality of life through clinic visits and phone calls.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction Down syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU de Bordeaux

    NOT_YET_RECRUITING

    Bordeaux, 33000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Centro di Medicina dell'Invecchiamento, Policlinico Universitario Agostino Gemelli IRCCS

    RECRUITING

    Roma, 00168, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Genetics department, Hospices Civils de Lyon

    NOT_YET_RECRUITING

    Lyon, 69500, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Genetics department, Institut Jérôme Lejeune

    RECRUITING

    Paris, 75725, France

    Contact Phone: •••-•••-••••

    Contact Email: •••••@•••••

    Contact

  • IRCCS Istituto Delle Scienze Neurologiche, Azienda Unita Sanitaria Locale Di Bologna

    RECRUITING

    Bologna, 40139, Italy

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Integrative Pharmacology and Systems Neurosciences, Hospital del Mar Research Institute

    RECRUITING

    Barcelona, 08003, Spain

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Service Génétique Médicale, CHU de Montpellier

    RECRUITING

    Montpellier, 34295, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Service de Génétique, Chromosomique et Moléculaire, Chu de Saint Etienne

    RECRUITING

    Saint-Etienne, 42270, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Servicio de Medicina Interna, Hospital Universitario De La Princesa

    NOT_YET_RECRUITING

    Madrid, 28006, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • UOR of Neurofarmacology and Translational Neurosciences, Associazione Oasi Maria S.S.Onlus

    RECRUITING

    Troina, 94018, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact