Diabetes combo trial pulled before it even started
NCT ID NCT07172867
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study was designed to test whether adding ofirnoflast to semaglutide helps obese people with type 2 diabetes control blood sugar and lose more weight than semaglutide alone. It was a Phase 2 trial planned for about 200 participants, but it was withdrawn before anyone enrolled. No results are available.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ofirnoflast (HT-6184) and semaglutide
What this could lead to
If it works, this combination could improve blood sugar control and weight loss more than semaglutide alone for people with type 2 diabetes and obesity.
What could go wrong
The trial was withdrawn before enrolling any participants, so no data exists. It is unclear if the combination would be safe or effective.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for OBESITY are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Cleveland Clinic Abu Dhabi
Abu Dhabi, Abu Dhabi Emirate, United Arab Emirates