Mayo clinic probes hidden link between belly fat and liver damage

NCT ID NCT04232566

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study from Mayo Clinic looks at how inflammation in fat tissue may affect the liver in people with severe obesity. Researchers will measure liver stiffness and fat tissue markers in 60 adults before they have weight-loss surgery. The goal is to better understand why some people develop nonalcoholic steatohepatitis (NASH) and insulin resistance.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could reveal why some people with obesity develop liver inflammation and scarring, pointing toward future prevention or treatment targets.
What could go wrong
This is an observational study, not a treatment trial. It will not directly improve health for participants and may not lead to any new therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mayo Clinic in Arizona

    RECRUITING

    Scottsdale, Arizona, 85259, United States

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Other studies related to the condition(s) this trial covers.