Mayo clinic probes hidden link between belly fat and liver damage

NCT ID NCT04232566

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study from Mayo Clinic looks at how inflammation in fat tissue may affect the liver in people with severe obesity. Researchers will measure liver stiffness and fat tissue markers in 60 adults before they have weight-loss surgery. The goal is to better understand why some people develop nonalcoholic steatohepatitis (NASH) and insulin resistance.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could reveal why some people with obesity develop liver inflammation and scarring, pointing toward future prevention or treatment targets.

What could go wrong

This is an observational study, not a treatment trial. It will not directly improve health for participants and may not lead to any new therapies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OBESITY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Insulin Resistance metabolic dysfunction-associated steatohepatitis metabolic dysfunction-associated steatotic liver disease morbid obesity Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mayo Clinic in Arizona

    RECRUITING

    Scottsdale, Arizona, 85259, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••