Scientists probe link between obesity and infertility

NCT ID NCT02653092

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study investigates how obesity-related factors like high insulin and fat levels may disrupt fertility in women. Researchers will measure hormone changes and metabolic responses in 84 women. The goal is to understand the underlying causes and inform future treatments to improve reproductive outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Insulin, Intralipid, Dextrose, Heparin, GnRH, and Hyperinsulinemic Euglycemic Clamp procedure

What this could lead to

If successful, this research could point toward new ways to improve fertility in women with obesity by targeting metabolic issues.

What could go wrong

This is an early observational study, not a treatment trial. It may not lead to direct benefits, and results may not apply to all women.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hyperinsulinism hypogonadotropic hypogonadism infertility disorder Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Colorado Denver

    Aurora, Colorado, 80045, United States