Scientists probe link between obesity and infertility

NCT ID NCT02653092

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study investigates how obesity-related factors like high insulin and fat levels may disrupt fertility in women. Researchers will measure hormone changes and metabolic responses in 84 women. The goal is to understand the underlying causes and inform future treatments to improve reproductive outcomes.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Insulin, Intralipid, Dextrose, Heparin, GnRH, and Hyperinsulinemic Euglycemic Clamp procedure
What this could lead to
If successful, this research could point toward new ways to improve fertility in women with obesity by targeting metabolic issues.
What could go wrong
This is an early observational study, not a treatment trial. It may not lead to direct benefits, and results may not apply to all women.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Colorado Denver

    Aurora, Colorado, 80045, United States

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