New weight loss shot tested in humans for first time

NCT ID NCT06737536

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested a new medicine called NNC0662-0419 in 100 adults who are overweight or obese. The main goal was to check if the drug is safe and how the body handles it. Participants received either the drug or a placebo as a weekly injection under the skin. This is the first time this medicine has been given to people.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
NNC0662-0419
What this could lead to
If this early trial shows the drug is safe, it could lead to a new weekly injection for weight management.
What could go wrong
This is a very early Phase 1 study with only 100 people. Many drugs fail at this stage, and it will take years to know if it works for weight loss.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Celerion, Lincoln

    Lincoln, Nebraska, 68502, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.