Probiotic tablets vs. mouthwash: a new way to fight gum disease?
NCT ID NCT07489924
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a probiotic tablet (Lactobacillus reuteri) can reduce harmful mouth bacteria as well as a standard chlorhexidine mouthwash in people with gum disease and type 2 diabetes. Twenty participants will use either the mouthwash or the probiotic for 30 days. The main goal is to see how much the bacteria Porphyromonas gingivalis decreases.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Chlorhexidine mouthwash and probiotic (Lactobacillus reuteri) tablets
What this could lead to
If successful, this could show that a simple probiotic tablet is as good as a mouthwash for controlling gum-disease bacteria in people with diabetes.
What could go wrong
This is a very small, early-phase trial with only 20 participants, so results may not apply to everyone. The probiotic might not work as well as the mouthwash.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Colima
Colima, 28040, Mexico