Heart scan may spot hidden brain disease
NCT ID NCT05514106
First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time
Summary
This study tests whether a special heart scan using a radioactive drug called 123I-MIBG can help identify Lewy body disease, a type of dementia that also affects movement and sleep. Researchers will compare scan results with clinical diagnoses in 50 people who have conditions like dementia, Parkinsonism, mild cognitive impairment, or REM sleep behavior disorder. The goal is to see if the scan can improve prediction of the underlying disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a radioactive drug called 123I-MIBG, given once for a heart scan
- What this could lead to
- If it works, this scan could become a reliable tool to diagnose Lewy body disease earlier and more accurately.
- What could go wrong
- This is a small, early-phase study, so the scan may not prove accurate enough for routine use. The radioactive drug carries a small radiation risk.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
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