Can metabolites fix cell power plants in septic shock?
NCT ID NCT04288635
First seen Dec 10, 2025 · Last updated Jun 20, 2026 · Updated 35 times
Summary
This study looks at whether adding certain natural substances (metabolites) to blood cells from septic shock patients can improve the function of mitochondria, the cell's power plants. Researchers will collect blood samples from 55 adults in the ICU and test different metabolites in the lab. The goal is to understand if this approach could one day lead to a treatment for the metabolic problems seen in septic shock.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CHU
RECRUITINGAngers, Maine et Loire, 49933, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this research could point toward a new treatment approach for septic shock by targeting mitochondrial dysfunction.
What could go wrong
This is a very early, small lab study using blood samples, not a treatment given to patients. It may not lead to any practical therapy.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.