Berry extract trial aims to stave off cognitive decline in At-Risk seniors
NCT ID NCT06507254
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a daily polyphenol supplement (like berry capsules) can slow cognitive decline in 300 older adults at risk for Alzheimer's. Participants take the supplement or a placebo for 12 months, providing blood, stool, and brain scans. The goal is to see if the supplement boosts brain-healthy gut bacteria and protects memory and thinking.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Polyphenol supplement (Juice Plus Essentials, Berry Blend Capsules)
- What this could lead to
- If it works, this could point toward a simple dietary supplement to help slow or prevent cognitive decline in older adults at risk for Alzheimer's disease.
- What could go wrong
- This is an early-stage study focused on measuring changes in gut bacteria and metabolites, not yet proving the supplement prevents dementia. The effect may be small or not translate to real-world benefits.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of California, Los Angeles
RECRUITINGLos Angeles, California, 90095, United States
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