Could a tiny dose of radiation ease your aching knees?
NCT ID NCT06887829
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether low-dose radiotherapy can reduce pain in people with knee osteoarthritis. 128 participants will receive either real radiation or a sham treatment three times a week for two weeks. Researchers will track pain scores and painkiller use for six months to see if the radiation helps more than the fake treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- low-dose radiotherapy (radiation)
- What this could lead to
- If it works, this could offer a new, non-drug option for easing chronic knee pain from osteoarthritis.
- What could go wrong
- This is an early-stage trial with only 128 people, so results may not apply widely. The treatment involves radiation, which carries small long-term risks, and the sham group helps check if benefits are real.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Mayo Clinic
RECRUITINGRochester, Minnesota, 55905, United States
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