Could a tiny dose of radiation ease your aching knees?

NCT ID NCT06887829

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether low-dose radiotherapy can reduce pain in people with knee osteoarthritis. 128 participants will receive either real radiation or a sham treatment three times a week for two weeks. Researchers will track pain scores and painkiller use for six months to see if the radiation helps more than the fake treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

low-dose radiotherapy (radiation)

What this could lead to

If it works, this could offer a new, non-drug option for easing chronic knee pain from osteoarthritis.

What could go wrong

This is an early-stage trial with only 128 people, so results may not apply widely. The treatment involves radiation, which carries small long-term risks, and the sham group helps check if benefits are real.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••