Gene therapy for knee pain: does it last?
NCT ID NCT05752032
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 16 people who previously received ICM-203 (a gene therapy) or a placebo for knee osteoarthritis. Researchers will track delayed side effects and measure changes in knee pain and function over time. The goal is to understand the long-term safety and effectiveness of this experimental treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ICM-203 (gene therapy)
What this could lead to
If successful, this could show that ICM-203 is safe and effective for long-term knee osteoarthritis control.
What could go wrong
This is a very small follow-up study (16 people) with no new treatment given, so results may not apply widely. Long-term safety data is still being collected.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for OSTEOARTHRITIS, KNEE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Barwon Health
Geelong, Victoria, 3220, Australia
-
Royal Adelaide Hospital
Adelaide, South Australia, 5000, Australia