Gene therapy for knee pain: does it last?
NCT ID NCT05752032
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 16 people who previously received ICM-203 (a gene therapy) or a placebo for knee osteoarthritis. Researchers will track delayed side effects and measure changes in knee pain and function over time. The goal is to understand the long-term safety and effectiveness of this experimental treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ICM-203 (gene therapy)
- What this could lead to
- If successful, this could show that ICM-203 is safe and effective for long-term knee osteoarthritis control.
- What could go wrong
- This is a very small follow-up study (16 people) with no new treatment given, so results may not apply widely. Long-term safety data is still being collected.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Barwon Health
Geelong, Victoria, 3220, Australia
-
Royal Adelaide Hospital
Adelaide, South Australia, 5000, Australia
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