New study tests brain games and nerve zap to clear long COVID fog and get people back to work

NCT ID NCT06095297

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two cognitive rehab programs for adults with long COVID who have mild to moderate brain fog. Both programs include computer games, in-lab training, and a mild nerve stimulation device worn on the ear. One group focuses on processing speed and work-related tasks, the other on relaxation and healthy habits. Researchers will measure thinking speed, daily function, and whether participants can return to work. The study is small (30 people) and results are expected to show if this approach is worth testing in larger trials.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
trans-auricular vagus nerve stimulation (taVNS)
What this could lead to
If successful, this could provide a practical, non-drug approach to reduce brain fog and help people with long COVID return to work.
What could go wrong
This is a small, early-stage trial with only 30 participants. The results may not apply to everyone with long COVID, and the benefits may be modest.

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Conditions

The condition(s) this trial relates to.

cognitive disorder Cognitive Dysfunction COVID-19 long COVID-19 Mental Fatigue

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Alabama at Birmingham

    RECRUITING

    Birmingham, Alabama, 35294, United States

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