Laser light may soothe chemo mouth pain in kids

NCT ID NCT02604329

Completed Symptom relief Sponsor: University Hospital, Toulouse Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a low-level laser can be used to treat painful mouth sores caused by chemotherapy or radiation in children with cancer. The laser was applied to the inside of the mouth every two days while sores were present. The main goal was to see if the treatment could be given at least three times in the first week. Only 22 children took part, and the study did not compare the laser to any other treatment, so it cannot say if the laser actually helps.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: low-level laser therapy (Oncolase Digi device)
What this could lead to: If this approach works, it could offer a non-drug way to ease mouth sore pain and speed healing in children undergoing cancer treatment.
What could go wrong: This is a very small feasibility study (22 children) with no control group, so it cannot prove effectiveness. The procedure may be difficult to apply consistently in young, sick children.

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Conditions

The condition(s) this trial relates to.

stomatitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ORAL MUCOSITIS

Contacts and locations

Locations

UH Toulouse

Toulouse, 31059, France

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