Knee pain breakthrough? PRP and stem cells face off in new trial

NCT ID NCT06893250

First seen Jun 20, 2026 · Last updated Jun 20, 2026

Summary

This study tests whether injections of platelet-rich plasma (PRP) or stem cells from belly fat can help people with knee osteoarthritis. 160 adults aged 40-70 with mild to moderate knee arthritis will be randomly assigned to get PRP, stem cells, both, or a placebo. Researchers will track pain, function, and MRI changes over two years to see which treatment works best.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University Hospital in Northern Norway

    Tromsø, Tromsø, 9038, Norway

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Platelet-rich plasma (PRP) and/or adipose tissue stem cells

What this could lead to

If successful, this could point toward a more effective, non-surgical treatment for knee osteoarthritis that reduces pain and improves function.

What could go wrong

This is a mid-stage trial with only 160 participants. It compares several treatments, so it may not clearly show which is best. Also, results may not apply to all patients with knee osteoarthritis.

Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.