Knee pain breakthrough? PRP and stem cells face off in new trial

NCT ID NCT06893250

ENROLLING_BY_INVITATION Disease control Sponsor: University Hospital of North Norway Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether injections of platelet-rich plasma (PRP) or stem cells from belly fat can help people with knee osteoarthritis. 160 adults aged 40-70 with mild to moderate knee arthritis will be randomly assigned to get PRP, stem cells, both, or a placebo. Researchers will track pain, function, and MRI changes over two years to see which treatment works best.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Platelet-rich plasma (PRP) and/or adipose tissue stem cells
What this could lead to: If successful, this could point toward a more effective, non-surgical treatment for knee osteoarthritis that reduces pain and improves function.
What could go wrong: This is a mid-stage trial with only 160 participants. It compares several treatments, so it may not clearly show which is best. Also, results may not apply to all patients with knee osteoarthritis.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEOARTHRITIS, KNEE

Contacts and locations

Locations

University Hospital in Northern Norway

Tromsø, Tromsø, 9038, Norway

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