Kidney cancer drug combo trial halted early

NCT ID NCT05935748

First seen Nov 12, 2025 · Last updated Apr 29, 2026 · Updated 20 times

Summary

This study tested a new drug (NKT2152) combined with two other medicines (palbociclib and sasanlimab) in people with advanced clear cell kidney cancer that had gotten worse after prior treatments. The goal was to see if the combination was safe and could shrink tumors. The trial was stopped early after enrolling 18 people, so results are limited.

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Contacts and locations

Locations

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065-6094, United States

  • Nebraska Cancer Specialists

    Omaha, Nebraska, 68130, United States

  • Northwestern University - Feinberg School of Medicine

    Chicago, Illinois, 60611, United States

  • UT Southwestern Medical Center

    Dallas, Texas, 75390-9324, United States

  • University of California San Diego

    La Jolla, California, 92093, United States

  • University of Michigan-Rogel Cancer Center

    Ann Arbor, Michigan, 48109, United States

  • University of Virginia Health System

    Charlottesville, Virginia, 22908, United States

Conditions

Explore the condition pages connected to this study.