Could a ketone drink give heart failure patients a boost?

NCT ID NCT06195982

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether a ketone drink can improve exercise ability in people with heart failure. Researchers will give 25 participants either the drink or a placebo before exercise tests. The goal is to see if the drink helps them exercise longer and with less shortness of breath.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ketone drink (ketone ester)

What this could lead to

If it works, this could point toward a simple dietary supplement to help heart failure patients exercise longer and feel less tired.

What could go wrong

This is a small, early-phase trial with only 25 people. The drink is experimental for this use, and results may not apply to all heart failure patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

heart failure Ketosis Motor Activity systolic heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Duke University

    Durham, North Carolina, 27710, United States