Ketone power: could a drink boost insulin sensitivity?
NCT ID NCT07359625
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a ketone supplement can improve how the body uses insulin and burns energy. Ten overweight adults aged 55-70 will receive different combinations of growth hormone, a ketone drink, or placebos on separate days. Using advanced PET scans and tissue samples, researchers will measure how ketones affect fat breakdown and glucose uptake. The goal is to understand the basic mechanisms, not yet to treat any disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Oral ketone supplement (D-β-hydroxybutyrate ester) and growth hormone infusion
- What this could lead to
- If successful, this could point toward using ketone supplements to improve insulin sensitivity and energy metabolism, potentially aiding in managing overweight and type 2 diabetes.
- What could go wrong
- This is a very small (10 participants), early-stage mechanistic study, not a treatment trial. Results may not translate to real-world benefits, and the interventions (growth hormone, ketones) may cause side effects.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Aarhus University Hospital
RECRUITINGAarhus N, 8200, Denmark
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