Ketone power: could a drink boost insulin sensitivity?

NCT ID NCT07359625

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a ketone supplement can improve how the body uses insulin and burns energy. Ten overweight adults aged 55-70 will receive different combinations of growth hormone, a ketone drink, or placebos on separate days. Using advanced PET scans and tissue samples, researchers will measure how ketones affect fat breakdown and glucose uptake. The goal is to understand the basic mechanisms, not yet to treat any disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Oral ketone supplement (D-β-hydroxybutyrate ester) and growth hormone infusion

What this could lead to

If successful, this could point toward using ketone supplements to improve insulin sensitivity and energy metabolism, potentially aiding in managing overweight and type 2 diabetes.

What could go wrong

This is a very small (10 participants), early-stage mechanistic study, not a treatment trial. Results may not translate to real-world benefits, and the interventions (growth hormone, ketones) may cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

disorder of fatty acid and ketone body metabolism Insulin Resistance Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Aarhus University Hospital

    RECRUITING

    Aarhus N, 8200, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••