Lung bath chemo during surgery aims to wipe out hidden sarcoma cells

NCT ID NCT02811523

Recruiting now Disease control Sponsor: University Health Network, Toronto Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tests a technique called in vivo lung perfusion (IVLP) that delivers chemotherapy directly into the lung during surgery to remove sarcoma tumors that have spread to the lungs. The goal is to kill any tiny cancer cells left behind that could cause the cancer to come back, while reducing side effects on the rest of the body. About 17 people with sarcoma in both lungs will take part. One lung will get the IVLP treatment and the other will receive standard care, so doctors can compare safety and effects.

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Conditions

The condition(s) this trial relates to.

bone cancer bone sarcoma metastatic neoplasm osteosarcoma sarcoma soft tissue sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BONE SARCOMA PULMONARY METASTASES SOFT TISSUE SARCOMA

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Princess Margaret Cancer Centre
RECRUITING

Toronto, Canada

Contact Phone: •••-•••-•••• Email: •••••@•••••