MRI study aims to uncover how brain small vessel disease progresses
NCT ID NCT05703386
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study at Johns Hopkins University will follow 50 people who have had a stroke and have risk factors like high blood pressure, high cholesterol, or diabetes. Researchers will use repeated MRI scans over about 15 months to track changes in the brain's white matter. The goal is to better understand how cerebral small vessel disease develops and leads to thinking and memory problems.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could reveal how small vessel disease in the brain leads to cognitive decline, pointing toward future prevention strategies.
- What could go wrong
- This is an observational imaging study, not a treatment trial. It may not directly lead to new therapies, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for DIABETES are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Kennedy Krieger Institute
RECRUITINGBaltimore, Maryland, 21205, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Zapping the brain to restore swallowing after stroke?
- Can Brain-Triggered stimulation reawaken arms after stroke?
- Can a few short nights of sleep tip the scales toward high blood pressure?
- Can lifestyle choices after a stroke extend life and prevent a second one?
- Chatbot could put blood pressure control in Patients' hands
- Can a 5-Step chat help tame high blood pressure?