HYPERLIPIDEMIAS

This study tests whether screening for social needs like housing and food access, combined with referrals to community resources, can improve chronic disease outcomes for patients of color. Researchers will track blood pressure, cholesterol, blood sugar, depression, and asthma co…

This study tests a program designed to help people with high blood pressure and high cholesterol lower their risk of heart disease. About 1,980 adults from Penn Medicine primary care clinics in West/Southwest Philadelphia and Lancaster will take part. The program uses tools and b…

This study tests a 24-week program called Black Impact for Black men with below-ideal heart health. Participants will take part in weekly physical activity, health education, and work with a coach and trainer. The goal is to see if the program improves heart health and reduces st…

This early-stage trial in 16 healthy adults tests whether a new drug for high cholesterol, HRS-1301, changes how the body processes two common medicines: midazolam (a sedative) and atorvastatin (a cholesterol drug). Participants will take these drugs alone and together with HRS-1…

This study looks at how a new cholesterol-lowering tablet, HRS-1301, behaves in people with mild, moderate, or severe kidney problems compared to healthy volunteers. The goal is to understand if kidney function changes how the drug works, so doctors can give the right dose. About…

This study at Johns Hopkins University will follow 50 people who have had a stroke and have risk factors like high blood pressure, high cholesterol, or diabetes. Researchers will use repeated MRI scans over about 15 months to track changes in the brain's white matter. The goal is…

This study looks at whether a protein called PCSK9, which helps control cholesterol, is linked to kidney damage in people with nephrotic syndrome. Researchers will measure PCSK9 levels in the blood and kidney tissue of 75 participants, comparing those with the condition to health…