Could a cholesterol protein worsen kidney disease? new study investigates

NCT ID NCT06373913

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looks at whether a protein called PCSK9, which helps control cholesterol, is linked to kidney damage in people with nephrotic syndrome. Researchers will measure PCSK9 levels in the blood and kidney tissue of 75 participants, comparing those with the condition to healthy controls. The goal is to better understand why high cholesterol occurs in nephrotic syndrome and whether PCSK9 plays a role in kidney injury.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help explain why high cholesterol occurs in nephrotic syndrome and point toward new ways to protect the kidneys.

What could go wrong

This is an early observational study with only 75 participants, so it cannot prove cause and effect. Results may not lead to any treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hyperlipidemia nephrotic syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Kolding Sygehus, Lillebælt Hospital

    RECRUITING

    Kolding, 6000, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-••••