NEPHROTIC SYNDROME

This study tests a drug called atacicept in 200 adults and teens with autoimmune kidney diseases like IgAN and FSGS. The goal is to see if it safely reduces protein in the urine and helps preserve kidney function. Participants must already be on standard treatments and weigh at l…

This study tests whether adding belimumab to rituximab works better than rituximab alone for people with membranous nephropathy, a kidney disease caused by the immune system attacking the kidneys. About 58 adults aged 18 to 75 with confirmed disease will receive either the combo …

This study is testing whether combining two immune-suppressing drugs, rituximab and cyclosporine, can safely and effectively treat membranous nephropathy, a kidney disease where the immune system attacks the kidneys, causing protein to leak into urine. About 30 adults with persis…

This study tests a smartphone app that helps people with kidney disease manage body swelling by giving daily instructions on adjusting their water pill (diuretic) dose. Thirty participants will use the app for 90 days, entering their weight and blood pressure daily. The goal is t…

This study aims to learn more about kidney diseases caused by the immune system, such as nephrotic syndrome and lupus nephritis. Researchers will follow up to 2,000 adults and children to track symptoms, responses to treatment, and collect blood or urine samples. The goal is to b…

This study looks at blood samples from 100 adults with a kidney condition called nephrotic syndrome. Researchers want to measure levels of certain immune markers (anti-nephrin autoantibodies) to see if they differ between types of the disease. The goal is to better understand the…

This study tests whether a smartphone app can help doctors and young adults (ages 16-29) with chronic kidney disease follow the latest treatment guidelines. The app provides reminders, education, and care recommendations. Researchers will check if using the app leads to better bl…

This study aims to see if a lab-grown cell system can detect a substance in the blood that causes protein leakage in the urine of people with a kidney condition called nephrotic syndrome. Researchers will compare blood and urine samples from 150 participants—including those with …

This study interviews 150 children, adults, and parents about their experiences with swelling caused by Nephrotic Syndrome. Researchers will use the information to create a survey that helps test new medications. No treatment is given; the goal is to better understand symptoms.

This study looks at whether a protein called PCSK9 is higher in people with nephrotic syndrome, a kidney condition that causes protein leakage and swelling. Researchers will compare blood and kidney tissue samples from 75 participants—some with the condition and some healthy—to s…