NEPHROTIC SYNDROME

This study is testing whether a smartphone app can help people with kidney problems better manage fluid buildup and swelling. Participants will use the app daily to track their weight and blood pressure, and it will provide personalized instructions for adjusting their water pill…

This study is testing an investigational drug called atacicept for several autoimmune kidney diseases, including IgA Nephropathy and Focal Segmental Glomerulosclerosis. It aims to see if weekly injections are safe and can reduce protein in the urine and help preserve kidney funct…

This study is testing whether combining two existing drugs, rituximab and cyclosporine, is safe and more effective for treating membranous nephropathy, an autoimmune disease that damages the kidneys' filters. The goal is to reduce harmful protein loss in urine and achieve lasting…

This study is testing if a combination of two immune-suppressing drugs works better than one to control primary membranous nephropathy, a serious autoimmune disease that damages the kidneys. It will enroll 58 adults to see if adding belimumab to rituximab leads to a more lasting …

This study aims to create a laboratory test that can detect harmful substances in the blood of people with a specific kidney disease called primary podocytopathy, which causes nephrotic syndrome. Researchers will compare blood and urine samples from 150 people—including patients …

This study aims to understand how a protein called PCSK9 might contribute to kidney damage and high cholesterol in people with nephrotic syndrome, a serious kidney condition. Researchers will compare PCSK9 levels in the blood and kidney tissue of 75 patients with the syndrome to …

This study aims to understand how swelling affects the daily lives of children and adults with Nephrotic Syndrome, a serious kidney disease. Researchers will conduct interviews with patients and parents to learn about their experiences. The information gathered will be used to cr…

This study aims to understand a specific type of kidney disease called idiopathic nephrotic syndrome by measuring certain antibodies in the blood. Researchers will analyze stored blood samples from 100 adults who have this condition, including some whose disease returned after a …

This National Institutes of Health study aims to better understand kidney diseases caused by immune system problems. Researchers will observe 2,000 patients with conditions like nephrotic syndrome and lupus nephritis to learn about disease patterns, symptoms, and treatment respon…