New combo therapy aims to calm overactive immune system in kidney disease
NCT ID NCT00977977
First seen Jan 03, 2026 · Last updated May 09, 2026 · Updated 19 times
Summary
This study is testing whether combining two immune-suppressing drugs, rituximab and cyclosporine, can safely and effectively treat membranous nephropathy, a kidney disease where the immune system attacks the kidneys, causing protein to leak into urine. About 30 adults with persistent protein in their urine will receive the drugs over 6 months and be monitored for up to 24 months. The goal is to reduce protein leakage and improve kidney health, though patients may need ongoing management.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
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National Naval Medical Center
RECRUITINGBethesda, Maryland, 20889, United States
Conditions
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