New combo therapy aims to tame kidney disease without Long-Term drugs
NCT ID NCT03949855
First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 31 times
Summary
This study tests whether adding belimumab to rituximab works better than rituximab alone for people with membranous nephropathy, a kidney disease caused by the immune system attacking the kidneys. About 58 adults aged 18 to 75 with confirmed disease will receive either the combo or rituximab alone. The goal is to see if the combo can reduce protein in urine and improve kidney function more effectively.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Columbia University Medical Center: Division of Nephrology
RECRUITINGNew York, New York, 10032, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Johns Hopkins
RECRUITINGBaltimore, Maryland, 21287, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mayo Clinic Jacksonville: Department of Nephrology and Hypertension
RECRUITINGJacksonville, Florida, 32224, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
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Ohio State University Wexner Medical Center: Division of Nephrology
RECRUITINGColumbus, Ohio, 43210, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Providence Medical Research Center, Providence Health Care: Nephrology
RECRUITINGSpokane, Washington, 99204, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Stanford University School of Medicine: Division of Nephrology
RECRUITINGStanford, California, 94305, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
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The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center:Division of Nephrology and Hypertension
RECRUITINGTorrance, California, 90502, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Alabama at Birmingham School of Medicine: Division of Nephrology
RECRUITINGBirmingham, Alabama, 35294, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Arkansas
RECRUITINGLittle Rock, Arkansas, 72205, United States
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University of California San Francisco
RECRUITINGSan Francisco, California, 94146, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Colorado
RECRUITINGAurora, Colorado, 80045, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Miami Miller School of Medicine, Div of Nephrology
RECRUITINGMiami, Florida, 33136, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Michigan
RECRUITINGAnn Arbor, Michigan, 48104, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Minnesota Health Clinical Research Unit
RECRUITINGMinneapolis, Minnesota, 55455, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Nebraska
RECRUITINGOmaha, Nebraska, 68198, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of North Carolina School of Medicine: Division of Nephrology and Hypertension, Kidney Center
RECRUITINGChapel Hill, North Carolina, 27599-, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Pennsylvania: Department of Medicine: Renal-Electrolyte and Hypertension Division
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Washington University in St. Louis
RECRUITINGSt Louis, Missouri, 63110, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Conditions
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