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Blood test may spot kidney disease relapse

NCT ID NCT06334692

Recruiting now Diagnosis Sponsor: Mario Negri Institute for Pharmacological Research Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at whether measuring certain antibodies in the blood can help diagnose and monitor idiopathic nephrotic syndrome, a kidney condition that causes swelling and protein loss. Researchers will test blood samples from 100 adults with different forms of the disease and compare them to controls. The goal is to see if these antibodies can reliably tell apart different types of nephrotic syndrome and possibly predict relapses.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Diagnostic test (ELISA) for anti-nephrin autoantibodies
What this could lead to
If successful, this test could help doctors diagnose certain types of nephrotic syndrome more accurately and possibly detect relapses earlier.
What could go wrong
This is a small, retrospective study that only measures antibody levels—it does not test a treatment. The test may not prove reliable enough for routine use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

focal segmental glomerulosclerosis idiopathic membranous glomerulonephritis lipoid nephrosis nephrotic syndrome primary focal segmental glomerulosclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NEPHROTIC SYNDROME

Contacts and locations

Locations

  • Clinical Research Center for Rare Disease Aldo e Cele Daccò

    RECRUITING

    Ranica, BG, 24020, Italy

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