New weekly shot aims to tackle high blood pressure and obesity together

NCT ID NCT07469800

First seen Apr 04, 2026 · Last updated Jun 23, 2026 · Updated 11 times

Summary

This Phase 3 trial tests a drug called IBI362 in people with mild to moderate high blood pressure who are also overweight or obese. Participants receive weekly injections of either the drug or a placebo for 48 weeks. The main goal is to see if IBI362 lowers blood pressure more than placebo at 16 weeks, with additional checks on weight loss and safety.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ruijin Hospital, Shanghai Jiaotong University School of Medicine

    RECRUITING

    Shanghai, Shanghai Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

IBI362 (a drug injected under the skin once a week)

What this could lead to

If it works, this could offer a new treatment option that lowers both blood pressure and body weight in people with hypertension and overweight or obesity.

What could go wrong

This is a Phase 3 trial, but it's still experimental. The drug may not work better than placebo, and side effects are possible. Results may not apply to everyone with hypertension.

Conditions

The condition(s) this trial relates to.

hypertensive disorder Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.