One pill to rule them all: new study aims to simplify heart failure treatment

NCT ID NCT07569640

Not yet recruiting Disease control Sponsor: Washington University School of Medicine Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 11, 2026 · Updated 3 times

Summary

This study tests whether a single pill containing four standard heart failure medications can help patients take their medicines more regularly and reduce hospitalizations and death. About 1,656 adults with heart failure and reduced pumping function will be randomly assigned to receive either the combination pill or usual care. The trial will track heart-related deaths, hospital stays, side effects, and quality of life over at least one year.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HEART FAILURE WITH REDUCED EJECTION FRACTION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

heart failure systolic heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE WITH REDUCED EJECTION FRACTION

Contacts and locations

Locations

Colombo North Teaching Hospital

Ragama, Western Province, 11010, Sri Lanka
Colombo South Teaching Hospital

Dehiwala, Western Province, 10350, Sri Lanka
District General Hospital Negombo

Negombo, Western Province, 11500, Sri Lanka
Gampaha District General Hospital

Gampaha, Western Province, 11000, Sri Lanka
National Hospital Galle

Galle, Southern Province, 80000, Sri Lanka
National Hospital Kandy

Kandy, Central Province, 20000, Sri Lanka
National Hospital of Sri Lanka

Colombo, Western Province, 00100, Sri Lanka
Teaching Hospital Jaffna

Jaffna, Northern Province, 40000, Sri Lanka
Teaching Hospital Kurunegala

Kurunegala, North Western Province, 60000, Sri Lanka
University Hospital - General Sir John Kotelawala Defence University

Colombo, Western Province, 10290, Sri Lanka

More trials for these conditions

Other studies related to the condition(s) this trial covers.