Scientists dig into gut bugs to unlock secrets of obesity and diabetes

NCT ID NCT05186389

Completed Knowledge-focused Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed study looked at gut bacteria in 90 adults with obesity, type 2 diabetes, or neither. Researchers collected samples from the small intestine and colon during routine endoscopies. They compared these to stool samples to see which bacteria are linked to metabolic health and inflammation. The goal is to better understand how gut microbes contribute to these diseases.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could identify specific gut bacteria that protect against or promote metabolic diseases like obesity and diabetes.
What could go wrong: This is an observational study with only 90 participants, so findings may not apply to everyone. It aims to understand, not treat, the disease.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

diabetes mellitus metabolic disease Obesity obesity disorder type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIABETES MELLITUS METABOLIC DISEASE OBESITY

Contacts and locations

Locations

Hôpital Privé des Peupliers, 8 Place de l'Abbé Georges Hénocque, 75013

Paris, France

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